RT Journal Article SR Electronic A1 Buckley, Rita T1 FDA Opens Door to Obesity Pharmacotherapy JF MD Conference Express YR 2013 FD SAGE Publications VO 13 IS 10 SP 14 OP 15 DO 10.1177/155989771310006 UL http://mdc.sagepub.com/content/13/10/14.abstract AB Obesity drugs have eluded the United States Food and Drug Administration (FDA) approval process for 13 years, but with mechanisms of action identified and obesity recognized as a disease, that is changing. This article reviews the history of obesity pharmacology, present options in obesity pharmacotherapy, as well as the discovery of peptide-based mixed agonists based on glucagon.