PT - JOURNAL ARTICLE AU - Buckley, Rita ED - Apovian, Caroline M. TI - FDA Opens Door to Obesity Pharmacotherapy DP - 2013 Nov 01 TA - MD Conference Express PG - 14--15 VI - 13 IP - 10 4099 - http://mdc.sagepub.com/content/13/10/14.short 4100 - http://mdc.sagepub.com/content/13/10/14.full AB - Obesity drugs have eluded the United States Food and Drug Administration (FDA) approval process for 13 years, but with mechanisms of action identified and obesity recognized as a disease, that is changing. This article reviews the history of obesity pharmacology, present options in obesity pharmacotherapy, as well as the discovery of peptide-based mixed agonists based on glucagon.