RT Journal Article SR Electronic A1 Lederman, Lynne T1 New Oral Anticoagulants Can Prevent Stroke Associated with Atrial Fibrillation JF MD Conference Express YR 2013 FD SAGE Publications VO 13 IS 14 SP 24 OP 25 DO 10.1177/155989771314014 UL http://mdc.sagepub.com/content/13/14/24.abstract AB Atrial fibrillation (AF), the most common cardiac arrhythmia, is associated with a 5-fold increased risk of stroke. Strokes related to AF are more severe and result in greater morbidity and mortality than strokes from other causes. This article reviews the historic role that vitamin K antagonists, particularly warfarin, have had in reducing the risk of stroke associated with AF.