RT Journal Article
SR Electronic
A1 Rizzo, Toni
T1 Oversupply of Free Fatty Acids to the Systemic Circulation is Not a Distinct Feature of Insulin Resistance or Obesity
JF MD Conference Express
YR 2013
FD SAGE Publications
VO 13
IS 16
SP 11
OP 12
DO 10.1177/155989771316009
UL http://mdc.sagepub.com/content/13/16/11.abstract
AB Measurements of free fatty acid (FFA), also known to as non-esterified fatty acid, and glucose kinetics have shown that obese individuals have adipose tissue that is insulin resistant [Jensen MD, Nielsen S. Metabolism 2007]. It is commonly thought that oversupply of FFA is a major contributor to the development of insulin resistance in obesity. This article discusses the known molecular mechanisms for the phenomenon of insulin resistance in adipose tissue and challenged the notion of oversupply of FFA in obesity.