RT Journal Article
SR Electronic
A1 Rizzo, Toni
T1 Hypertrophic Obesity is Associated with Inflammation and Insulin Resistance
JF MD Conference Express
YR 2013
FD SAGE Publications
VO 13
IS 16
SP 10
OP 11
DO 10.1177/155989771316008
UL http://mdc.sagepub.com/content/13/16/10.2.abstract
AB Obesity causes changes in adipose tissue, the liver, and skeletal muscle that lead to systemic inflammation and insulin resistance. Obese individuals who have the ability to recruit new adipocytes develop adipocyte hyperplasia, whereas others have adipocyte hypertrophy due to impaired adipogenesis. The ability to recruit new adipocytes protects against ectopic fat accumulation in the abdomen, skeletal muscle, and liver.