RT Journal Article SR Electronic A1 Kuznar, Wayne T1 Glycemic Improvement with Canagliflozin is Durable in T2DM Patients on Metformin JF MD Conference Express YR 2013 FD SAGE Publications VO 13 IS 17 SP 24 OP 25 DO 10.1177/155989771317016 UL http://mdc.sagepub.com/content/13/17/24.abstract AB The sodium glucose cotransporter 2 inhibitor canagliflozin is associated with durable glycemic improvement over 104 weeks compared with glimepiride in patients with type 2 diabetes mellitus (T2DM) on background metformin therapy. Such was the primary finding of a Phase 3 randomized, double-blind efficacy and safety study.