Summary

Patients with symptomatic intracranial hemorrhage (sICH) have an increased risk of a poor or fatal outcome [Strbian D et al. Neurology 2011]. However, the direct comparison of sICH rates between different thrombolysis studies is complicated by varying definitions of sICH [Gumbinger C. et al. Stroke 2012]. This article discusses results from a study on the most accurate definition of clinically relevant hemorrhagic transformation after thrombolytic therapy for stroke with IV tissue plasminogen activator.