PT - JOURNAL ARTICLE AU - Vinall, Maria ED - Büller, Harry R. TI - Oral Rivaroxaban Alone for Symptomatic Pulmonary Embolism DP - 2012 Jun 01 TA - MD Conference Express PG - 21--22 VI - 12 IP - 4 4099 - http://mdc.sagepub.com/content/12/4/21.short 4100 - http://mdc.sagepub.com/content/12/4/21.full AB - Rivaroxaban, a direct, specific, competitive factor Xa inhibitor that inhibits thrombin generation, is an effective treatment for venous thromboembolism. The Oral Direct Factor Xa Inhibitor Rivaroxaban in Patients With Acute Symptomatic Deep-Vein Thrombosis or Pulmonary Embolism trial [EINSTEIN PE; Buller HR et al. N Engl J Med 2012] reported data that showed that rivaroxaban was noninferior to standard therapy but had a superior bleeding profile in patients with pulmonary embolism.