PT - JOURNAL ARTICLE AU - Vinall, Maria ED - Morrow, David A. TI - Evaluation of a Novel Antiplatelet Agent for Secondary Prevention in Patients with Atherosclerotic Disease: Results from the TRA 2P-TIMI 50 Trial DP - 2012 Jun 01 TA - MD Conference Express PG - 19--19 VI - 12 IP - 4 4099 - http://mdc.sagepub.com/content/12/4/19.1.short 4100 - http://mdc.sagepub.com/content/12/4/19.1.full AB - In stable patients with a history of atherosclerosis, the investigational protease-activated receptor (PAR)-1 antagonist vorapaxar was effective at reducing further atherothrombotic events. This article presents data from the Thrombin Receptor Antagonist in Secondary Prevention-TIMI 50 Trial [TRA 2P; NCT00526474] which showed that vorapaxar significantly reduced the risk of deaths from cardiovascular disease, myocardial infarction, or stroke compared with placebo.