PT  - JOURNAL ARTICLE
AU  - Rizzo, Toni
ED  - Baraliakos, Xenofon
TI  - Inflammation and Fatty Degeneration in New Bone Formation in Patients with AS Treated with Anti-TNF Agents
DP  - 2012 Sep 01
TA  - MD Conference Express
PG  - 19--20
VI  - 12
IP  - 9
4099  - http://mdc.sagepub.com/content/12/9/19.short
4100  - http://mdc.sagepub.com/content/12/9/19.full
AB  - When the inflammation of ankylosing spondylitis (AS) subsides, it may be replaced by repair tissue and fatty lesions, a process that leads to osteoproliferation and development of syndesmophytes. This article presents results from the European Ankylosing Spondylitis Infliximab Cohort [EASIC] study, an open-label extension of the Ankylosing Spondylitis Study for the Evaluation of Recombinant Infliximab Therapy [ASSERT]. The objective of the EASIC study was to directly compare the effect of inflammation and fatty degeneration on the development of syndesmophytes in patients with AS after 5 years of anti-TNF therapy.