RT Journal Article SR Electronic A1 Vinall, Maria T1 The ASTIS Trial: First Results JF MD Conference Express YR 2012 FD SAGE Publications VO 12 IS 9 SP 8 OP 8 DO 10.1177/155989771209004 UL http://mdc.sagepub.com/content/12/9/8.1.abstract AB This article discusses the first results from the Autologous Stem Cell Transplantation International Scleroderma trial [ASTIS; ISRCTN54371254], an international, investigator-initiated, open-label Phase 3 trial that suggests that hematopoietic stem cell transplantation results in better long-term event-free and overall survival compared with conventional treatment for patients with poor prognosis, early diffuse, cutaneous systemic sclerosis.