PT - JOURNAL ARTICLE AU - Vinall, Maria ED - van Laar, Jacob M. TI - The ASTIS Trial: First Results DP - 2012 Sep 01 TA - MD Conference Express PG - 8--8 VI - 12 IP - 9 4099 - http://mdc.sagepub.com/content/12/9/8.1.short 4100 - http://mdc.sagepub.com/content/12/9/8.1.full AB - This article discusses the first results from the Autologous Stem Cell Transplantation International Scleroderma trial [ASTIS; ISRCTN54371254], an international, investigator-initiated, open-label Phase 3 trial that suggests that hematopoietic stem cell transplantation results in better long-term event-free and overall survival compared with conventional treatment for patients with poor prognosis, early diffuse, cutaneous systemic sclerosis.