PT - JOURNAL ARTICLE AU - Vinall, Phil ED - Bolli, Geremia B. TI - Update on Basal and Bolus Insulin Therapies DP - 2012 Sep 01 TA - MD Conference Express PG - 22--23 VI - 12 IP - 10 4099 - http://mdc.sagepub.com/content/12/10/22.short 4100 - http://mdc.sagepub.com/content/12/10/22.full AB - Insulin is released continuously by the pancreas at a nearly constant rate between meals and in the fasting state (basal insulin secretion). This article discusses the data on various basal insulins, as well as evolution of rapid-acting insulin, limitations of current insulin preparations, and pipeline products.