RT Journal Article
SR Electronic
A1 Vinall, Phil
T1 The Precocious “AGE'ing” Effect of Type 1 Diabetes in Children
JF MD Conference Express
YR 2012
FD SAGE Publications
VO 12
IS 10
SP 10
OP 10
DO 10.1177/155989771210004
UL http://mdc.sagepub.com/content/12/10/10.1.abstract
AB Type 1 diabetes mellitus increases the formation of long-lived complexes, known as advanced glycation endproducts (AGEs), which can contribute to the development of complications in patients with diabetes [Genuth S et al. Diabetes 2005]. AGEs accumulate naturally in tissues over time, and tissue burden is a function of chronological age. This article presents results of the “The Precocious “AGE—ing” Effect of Type 1 Diabetes in Children” study, which examined the relationship between chronological age and type 1 diabetes on skin AGEs in children.