RT Journal Article
SR Electronic
A1 Rizzo, Toni
T1 Inflammation and Vascular Injury
JF MD Conference Express
YR 2012
FD SAGE Publications
VO 12
IS 3
SP 17
OP 18
DO 10.1177/155989771203015
UL http://mdc.sagepub.com/content/12/3/17.abstract
AB The focus this article is on a class of leukocyte adhesion molecules, leukocyte β2-integrins, among which Mac-1 (aMb2, CD11b/CD18) is the most common integrin on neutrophils. The leukocyte Mac-1 receptor interacts with the glyocoprotein Iba (GPIba) receptor on platelets, thereby regulating pro-inflammatory and pro-thrombotic bidirectional signals in both inflammatory cells and platelets.