RT Journal Article
SR Electronic
A1 Rizzo, Toni
T1 DPP-4 in Diabetic Cardiomyopathy
JF MD Conference Express
YR 2012
FD SAGE Publications
VO 12
IS 3
SP 8
OP 9
DO 10.1177/155989771203005
UL http://mdc.sagepub.com/content/12/3/8.2.abstract
AB Dipeptidyl peptidase-4 (DPP-4) is a serine exoprotease that is expressed on the surface of many cells. DPP-4 truncates bioactive molecules, including incretin and nonincretin substrates. This article discusses the effect of DPP-4 inhibition on chronic myocardial remodeling and dysfunction associated with diabetes.