RT Journal Article SR Electronic A1 Buckley, Rita T1 Echo-Guided Left Ventricular Lead Placement Improves CRT Response JF MD Conference Express YR 2012 FD SAGE Publications VO 12 IS 6 SP 7 OP 8 DO 10.1177/155989771206002 UL http://mdc.sagepub.com/content/12/6/7.abstract AB Cardiac resynchronization therapy (CRT) improves mortality and morbidity in heart failure patients with depressed ejection fraction and wide QRS complex, but response varies, with about one third of CRT recipients failing to improve. The Speckle Tracking-Assisted Resynchronization Therapy for Electrode Region trial [STARTER] tested the hypothesis that echo-guided left ventricular (LV) lead placement that targets the site of latest LV mechanical activation is superior to routine positioning for CRT.