RT Journal Article SR Electronic A1 Rizzo, Toni T1 Implications of Angiotensin II Receptor Blockade in the Progression of Atherosclerotic Vascular Disease JF MD Conference Express YR 2012 FD SAGE Publications VO 12 IS 12 SP 12 OP 13 DO 10.1177/155989771212005 UL http://mdc.sagepub.com/content/12/12/12.abstract AB Atherosclerosis is caused by the combined effect of lipid infiltration and inflammatory cytokine activation in large and medium arterial walls. A direct correlation exists between coronary heart disease, vascular disease, and atherosclerosis with risk thresholds starting at very low or normal risk factor levels. This article discusses the angiotensin receptor blockade, as well how to target the renin-angiotensin-aldosterone system for atherosclerotic vascular disease, vascular remodeling, and hypertension.