PT - JOURNAL ARTICLE AU - Buckley, Rita ED - Krucoff, Mitchell W. TI - Novel Design Changes in DES Not Necessarily Better until Proven So DP - 2012 Dec 01 TA - MD Conference Express PG - 24--24 VI - 12 IP - 8 4099 - http://mdc.sagepub.com/content/12/8/24.short 4100 - http://mdc.sagepub.com/content/12/8/24.full AB - A drug-eluting stent is a “combination product” in which changes to one component may affect others; small alterations to strut thickness and geometry, polymer, drug, dose, and kinetics may result in big outcome changes, for better or worse. This article discusses the many factors involved in the development and deployment of novel stents.