RT Journal Article
SR Electronic
A1 Nichols, Emma Hitt
T1 How to Integrate New Drugs into the Current Therapeutic Landscape of Metastatic Triple-Negative Breast Cancer
JF MD Conference Express
YR 2012
FD SAGE Publications
VO 12
IS 15
SP 22
OP 24
DO 10.1177/155989771215016
UL http://mdc.sagepub.com/content/12/15/22.abstract
AB This article reviews the main reasons why drugs fail in triple-negative breast cancer (TNBC) and targeted agents for the treatment of TNBC, as well as discusses ways that molecular triaging can assist in the selection of patients for clinical trials, the role of new cytotoxic agents in TNBC, and angiogenic vascular cells, infiltrating immune cells, and cancer-associated fibroblasts, and adipocytes as host components