PT - JOURNAL ARTICLE AU - Nichols, Emma Hitt ED - Machiels, Jean-Pascal TI - Biologically Based Treatment in Head and Neck Squamous Cell Carcinoma DP - 2012 01 TA - MD Conference Express PG - 16--17 VI - 12 IP - 15 4099 - http://mdc.sagepub.com/content/12/15/16.short 4100 - http://mdc.sagepub.com/content/12/15/16.full AB - This article discusses the concept of window-of-opportunity studies in relation to squamous cell cancers of the head and neck. Also discussed are predictors of sensitivity and resistance mechanisms, a review of poly (adenosine diphosphate-ribose) polymerase inhibitors and strategies in chemoradiation.