RT Journal Article
SR Electronic
A1 Rizzo, Toni
T1 Single-Agent Doxorubicin versus Doxorubicin Plus Ifosfamide in Advanced Soft Tissue Sarcoma
JF MD Conference Express
YR 2012
FD SAGE Publications
VO 12
IS 15
SP 9
OP 10
DO 10.1177/155989771215005
UL http://mdc.sagepub.com/content/12/15/9.2.abstract
AB Patients with locally advanced unresectable or metastatic soft tissue sarcoma have poor outcomes. Palliative chemotherapy is standard treatment for these patients, but it generally results in considerable toxicity. Previous studies have compared single-agent doxorubicin with doxorubicin plus ifosfamide, but the optimal doses remain unclear. This article discusses the European Organisation for Research and Treatment of Cancer 62012 Phase 3 study [NCT00061984] in patients with advanced soft tissue sarcoma.