RT Journal Article SR Electronic A1 Vinall, Phil T1 A Paradigm Shift in Early Drug Development: Individualizing to More Patient Benefit JF MD Conference Express YR 2012 FD SAGE Publications VO 12 IS 15 SP 6 OP 7 DO 10.1177/155989771215002 UL http://mdc.sagepub.com/content/12/15/6.abstract AB With the increasing the use of biomarkers in cancer treatment, the emphasis on selecting the right treatment for the right patient takes on added significance in early drug development. This article discusses the difficulties inherent in selecting patients for early drug-development studies.