RT Journal Article
SR Electronic
A1 Alexander, Lori
T1 Hyporesponsiveness to Clopidogrel Does Not Predict 1-Year Mortality
JF MD Conference Express
YR 2012
FD SAGE Publications
VO 12
IS 17
SP 22
OP 23
DO 10.1177/155989771217010
UL http://mdc.sagepub.com/content/12/17/22.abstract
AB An analysis from the Assessment of Dual Antiplatelet Therapy with Drug-Eluting Stents [ADAPT-DES; NCT00638794] trial showed that hyporesponsiveness to clopidogrel was not independently predictive of mortality at 1-year after percutaneous coronary intervention with a drug-eluting stent. Although hyporesponsiveness to clopidogrel was associated with increased risk of stent thrombosis and myocardial infarction, it was also associated with a reduced risk of major bleeding, which has been strongly related to mortality.