RT Journal Article
SR Electronic
A1 Vinall, Maria
T1 IMPROVED: Final Study Results of Combination Treatment in Patients with Early RA and UA
JF MD Conference Express
YR 2012
FD SAGE Publications
VO 12
IS 19
SP 17
OP 18
DO 10.1177/155989771219013
UL http://mdc.sagepub.com/content/12/19/17.abstract
AB Final results of the Induction Therapy with Methotrexate and Prednisone in Rheumatoid or Very Early Arthritis Disease [IMPROVED] study showed that patients with rheumatoid arthritis and undifferentiated arthritis achieved similarly greater rates of remission after early initial treatment with combination therapy (methotrexate and prednisone). Patients who failed to achieve early remission benefited more when switched to a treatment strategy with adalimumab than with multiple disease modifying antirheumatic drugs, with virtually no radiographic damage progression in all patients.