RT Journal Article
SR Electronic
A1 Kuznar, Wayne
T1 Genetic Variations Do Not Account for Variable Response to Mycophenolate Mofetil in Lupus Nephritis
JF MD Conference Express
YR 2012
FD SAGE Publications
VO 12
IS 19
SP 10
OP 11
DO 10.1177/155989771219005
UL http://mdc.sagepub.com/content/12/19/10.2.abstract
AB Genetic testing for variants of inosine monophosphate dehydrogenase isoforms will not predict clinical response to mycophenolate mofetil (MMF) in the treatment of lupus nephritis. The Study of Mycophenolate Mofetil in Management of Patients with Lupus Nephritis [ALMS] demonstrated the efficacy of MMF for induction and maintenance of response in lupus nephritis, but response was not uniform, leading to a search for predictors of efficacy.