RT Journal Article SR Electronic A1 Buckley, Rita T1 Intensive Lifestyle Intervention and Metformin are Cost-Effective for Diabetes Prevention JF MD Conference Express YR 2011 FD SAGE Publications VO 11 IS 8 SP 14 OP 14 DO 10.1177/155989771108008 UL http://mdc.sagepub.com/content/11/8/14.abstract AB The Diabetes Prevention Program (DPP) was a multicenter trial that examined the impact of an intensive lifestyle intervention or metformin to prevent or delay the development of diabetes in a high-risk population with impaired glucose tolerance. The DPP ended early, demonstrating that lifestyle modification reduced diabetes onset by 58% versus 31% by metformin [Diabetes Prevention Program Research Group. N Engl J Med 2002].