RT Journal Article SR Electronic A1 Alexander, Lori T1 Novel Agent Found to Reduce HbA1C in Type 2 Diabetes JF MD Conference Express YR 2011 FD SAGE Publications VO 11 IS 8 SP 13 OP 14 DO 10.1177/155989771108007 UL http://mdc.sagepub.com/content/11/8/13.abstract AB A randomized, double-blind, multicenter study demonstrated that a G-protein-coupled receptor 40 (GPR40) agonist had glucose-lowering efficacy for the treatment of type 2 diabetes. The novel agent significantly reduced HbA1C compared with placebo, with efficacy that was comparable with glimepiride but with a significantly lower rate of hypoglycemia.