RT Journal Article
SR Electronic
A1 Vinall, Maria
T1 Controversial Issues in TAVI
JF MD Conference Express
YR 2011
FD SAGE Publications
VO 11
IS 10
SP 27
OP 28
DO 10.1177/155989771110018
UL http://mdc.sagepub.com/content/11/10/27.abstract
AB There are three major accepted indications for transcatheter aortic valve implantation (TAVI), as well as a number of minor conditions in which TAVI may be reasonable. The first is an inoperable patient with severe aortic stenosis (mean gradient >40 mm Hg or jet velocity >4 m/sec) and surgical risk >50%. The benefit of TAVI in these patients was shown in the PARTNER trial [NCT00530894; Leon MB et al. N Engl J Med 2010], which reported a cardiovascular mortality rate after 1 year of 20.5% for TAVI patients versus 44.6% for patients who received standard therapy (p<0.001).