RT Journal Article SR Electronic A1 Vinall, Maria T1 Safety and Tolerability Darexaban in Patients with ACS: The RUBY-1 Trial JF MD Conference Express YR 2011 FD SAGE Publications VO 11 IS 10 SP 13 OP 14 DO 10.1177/155989771110005 UL http://mdc.sagepub.com/content/11/10/13.abstract AB Results from the RUBY-I trial [NCT00994292] showed a dose-related, 2- to 4-fold increase in bleeding when the factor Xa inhibitor darexaban was added to standard treatment (aspirin with or without clopidogrel) for the secondary prevention of ischemic vascular events in patients with recent acute coronary syndrome.