RT Journal Article SR Electronic A1 Buckley, Rita T1 Novel Biochemical Concepts behind Late Diabetic Complications JF MD Conference Express YR 2011 FD SAGE Publications VO 11 IS 11 SP 31 OP 31 DO 10.1177/155989771111019 UL http://mdc.sagepub.com/content/11/11/31.abstract AB Diabetes has a devastating systemic impact on those who suffer from it, including a 2- to 4-fold increase in cardiovascular events and stroke, nontraumatic lower extremity amputations, end-stage renal disease, and blindness in working age adults. These outcomes underscore the importance of identifying novel pathways that lead to late diabetic complications.