PT - JOURNAL ARTICLE AU - Buckley, Rita ED - Prabhakar, Nanduri R. TI - Intermittent Hypoxia — A Sleep Apnea Model DP - 2011 Dec 01 TA - MD Conference Express PG - 23--24 VI - 11 IP - 11 4099 - http://mdc.sagepub.com/content/11/11/23.short 4100 - http://mdc.sagepub.com/content/11/11/23.full AB - From 1986 to 2002, sleep apnea affected >100 million individuals worldwide [WHO; Chronic Respiratory Diseases]. Apneas lead to periodic desaturation of O2 in arterial blood. In severe cases, O2 saturation drops to nearly 50%, and the frequency of apneas can reach as many as 60 to 90 episodes per hour. This article discusses the effects of intermittent hypoxia on glucose homeostasis.