PT - JOURNAL ARTICLE AU - Vinall, Maria ED - Leifke, Eckhard TI - TAK-875 Reduces HbA1C in Patients with T2DM DP - 2011 Dec 01 TA - MD Conference Express PG - 10--10 VI - 11 IP - 11 4099 - http://mdc.sagepub.com/content/11/11/10.short 4100 - http://mdc.sagepub.com/content/11/11/10.full AB - TAK-875 is a selective G-protein-coupled receptor 40 (GPR40) agonist that is being developed as an adjunct therapy to diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus. Results of a Phase 2 [NCT01007097] trial that has shown the glucose-lowering efficacy, safety, and tolerability of TAK-875 in a clinical setting are discussed.