RT Journal Article SR Electronic A1 Butterman, Eric T1 New Drugs on the Horizon to Treat MDR Pathogens JF MD Conference Express YR 2011 FD SAGE Publications VO 11 IS 12 SP 25 OP 26 DO 10.1177/155989771112015 UL http://mdc.sagepub.com/content/11/12/25.abstract AB Aminoglycosides are a well-known class of drugs with proven efficacy; however, they are being used less frequently because of resistance, nephrotoxicity, and ototoxicity. This article discusses plazomicin (formerly ACHN-490), a new aminoglycoside that is used to treat gram-negative infections.