PT - JOURNAL ARTICLE AU - Butterman, Eric ED - Steenbergen, Judith TI - CXA-201 Effective against Common ICU Pathogens, Including MDR Gram-Negative Pathogens and Pseudomonas aeruginosa DP - 2011 Dec 01 TA - MD Conference Express PG - 10--11 VI - 11 IP - 12 4099 - http://mdc.sagepub.com/content/11/12/10.short 4100 - http://mdc.sagepub.com/content/11/12/10.full AB - Using a pharmacokinetic/pharmacodynamic (PK/PD) target algorithm, the in vitro potency of CXA-201 (CXA101/tazobactam), a novel cephalosporin and b-lactamase inhibitor combination that is being developed to treat serious bacterial infections, was reported to be lower in isolates from the intensive care unit (ICU) compared with non-ICU isolates.