PT - JOURNAL ARTICLE AU - Sinclair, Heather Q. ED - Held, Claes TI - Ticagrelor May Be an Effective Alternative to Clopidogrel in Patients with ACS Who Subsequently Undergo CABG DP - 2010 May 01 TA - MD Conference Express PG - 19--20 VI - 10 IP - 2 4099 - http://mdc.sagepub.com/content/10/2/19.short 4100 - http://mdc.sagepub.com/content/10/2/19.full AB - In patients with acute coronary syndrome (ACS) who are undergoing coronary artery bypass grafting (CABG), treatment with ticagrelor within 7 days prior to surgery is associated with lower rates of mortality after CABG and comparable rates of CABG-related bleeding compared with clopidogrel. Findings from a retrospective analysis of the nonrandomized subgroup of patients who required CABG (n=1261) within 7 days of last intake of study drug from the Platelet Inhibition and Patient Outcomes [PLATO; NCT00391872] study, comparing ticagrelor and clopidogrel.