PT - JOURNAL ARTICLE AU - Sinclair, Heather Q. ED - Patkar, Ashwin TI - Ziprasidone Therapy in the Acute Depressive Mixed State DP - 2010 Aug 01 TA - MD Conference Express PG - 11--11 VI - 10 IP - 4 4099 - http://mdc.sagepub.com/content/10/4/11.short 4100 - http://mdc.sagepub.com/content/10/4/11.full AB - Ziprasidone demonstrated efficacy and tolerability among patients with depressive mixed state, according to a recent study. In this double-blind, placebo-controlled, multicenter trial that included 74 patients who met DSM-IV criteria for major depressive disorder and two to three DSM-IV mania criteria, patients were randomized to receive either ziprasidone 40–160 mg/daily (n=36) or placebo (n=38) for 6 weeks in a forced titration regimen.