RT Journal Article SR Electronic A1 Sinclair, Heather Q. T1 Neurobiologic and Psychopharmacologic Solutions for the Treatment of Depression JF MD Conference Express YR 2010 FD SAGE Publications VO 10 IS 4 SP 7 OP 9 DO 10.1177/155989771004002 UL http://mdc.sagepub.com/content/10/4/7.abstract AB Antidepressant treatment response is dependent upon numerous individual factors, such as gender, age, disease severity, symptom type, comorbidities, and genetic factors. New advances in pharmacogenetics, neurosurgical intervention, and medications may hold the key to improving treatment response in patients with refractory depression.