PT - JOURNAL ARTICLE ED - Nakao, Kazuwa TI - Candesartan and Amlodipine: Effect on the Incidence of Cardiovascular Events and New-Onset Diabetes DP - 2010 Nov 01 TA - MD Conference Express PG - 12--12 VI - 10 IP - 5 4099 - http://mdc.sagepub.com/content/10/5/12.1.short 4100 - http://mdc.sagepub.com/content/10/5/12.1.full AB - The 3-year extension of the Candesartan Antihypertensive Survival Evaluation in Japan [CASE-J] Study demonstrated comparable efficacy of the angiotensin receptor blocker candesartan and the calcium channel blocker amlodipine on the incidence of cardiovascular events in high-risk hypertensive Japanese patients. As observed in the earlier phase of the study, cadesartan exhibited sustained superiority over amlodipine with regards to reduction in new-onset diabetes throughout the 3-year extended follow up.