PT  - JOURNAL ARTICLE
AU  - Vinall, Maria
ED  - Nesto, Richard W.
TI  - No Significant Benefit with Rosiglitazone in Preventing Progression of Atherosclerosis in Diabetic Patients with a History of Cardiovascular Disease
DP  - 2009 Feb 01
TA  - MD Conference Express
PG  - 21--22
VI  - 8
IP  - 8
4099  - http://mdc.sagepub.com/content/8/8/21.short
4100  - http://mdc.sagepub.com/content/8/8/21.full
AB  - Thiazolidinediones, such as rosiglitazone, have been shown to increase insulin sensitivity and reduce other cardiovascular risk factors but increase fluid retention and the risk of heart failure. This article discusses results of the Assessment on the Prevention of Progression by Rosiglitazone on Atherosclerosis in Diabetes Patients with Cardiovascular History [APPROACH; NCT00116831] trial.