RT Journal Article
SR Electronic
A1 Vinall, Maria
T1 Issues in Pediatric Stroke
JF MD Conference Express
YR 2009
FD SAGE Publications
VO 9
IS 1
SP 27
OP 28
DO 10.1177/155989770901017
UL http://mdc.sagepub.com/content/9/1/27.abstract
AB Cerebral arteriopathy is the strongest predictor of recurrent arterial ischemic stroke (AIS) in childhood [Fullerton HJ et al. Pediatrics 2007]. This article discusses results from the International Pediatric Stroke Study [IPSS], which suggest a role for infection in the pathogenesis of cerebral arteriopathy. Also discussed are the results of a retrospective study that showed that circulating endothelial cells can be used to track cerebral arteriopathy-associated vascular injury and to differentiate progressive versus nonprogressive disease in children with AIS.