PT - JOURNAL ARTICLE AU - Vinall, Maria ED - Hills, Nancy K. TI - Issues in Pediatric Stroke DP - 2009 Apr 01 TA - MD Conference Express PG - 27--28 VI - 9 IP - 1 4099 - http://mdc.sagepub.com/content/9/1/27.short 4100 - http://mdc.sagepub.com/content/9/1/27.full AB - Cerebral arteriopathy is the strongest predictor of recurrent arterial ischemic stroke (AIS) in childhood [Fullerton HJ et al. Pediatrics 2007]. This article discusses results from the International Pediatric Stroke Study [IPSS], which suggest a role for infection in the pathogenesis of cerebral arteriopathy. Also discussed are the results of a retrospective study that showed that circulating endothelial cells can be used to track cerebral arteriopathy-associated vascular injury and to differentiate progressive versus nonprogressive disease in children with AIS.