PT - JOURNAL ARTICLE AU - Vinall, Phil ED - Kleindorfer, Dawn TI - Eligibility for rt-PA within a Population: The Effect of the ECASS-3 Trial DP - 2009 Apr 01 TA - MD Conference Express PG - 21--21 VI - 9 IP - 1 4099 - http://mdc.sagepub.com/content/9/1/21.short 4100 - http://mdc.sagepub.com/content/9/1/21.full AB - According to standard emergency department (ED) guidelines, ischemic stroke patients must present to an ED within <3 hours of symptom onset to be eligible for rt-PA therapy. The European Cooperative Acute Stroke Study-3 [ECASS-3] expanded this eligibility window to 4.5 hours but with additional exclusion criteria. Even with this expanded time window, eligibility for rt-PA remains low—about 9% versus 8% for the older time window.