RT Journal Article
SR Electronic
A1 Vinall, Maria
T1 Options for Treatment-Resistant Depression
JF MD Conference Express
YR 2009
FD SAGE Publications
VO 9
IS 3
SP 15
OP 16
DO 10.1177/155989770903005
UL http://mdc.sagepub.com/content/9/3/15.abstract
AB Only about 50% of patients with major depressive disorder will respond after their first treatment, and of these responders, only 50% to 70% will achieve symptom remission [Rush AJ et al. Am J Psychiatry 2003]. This article discusses several pharmacological strategies that are used in patients whose depression is resistant to treatment after optimized monotherapy has been attempted, as well as several of the somatic treatments that are emerging as options.