RT Journal Article SR Electronic A1 Jacobson, Anne T1 Irbesartan Fails to Prevent Most Vascular Events in Patients with AF JF MD Conference Express YR 2009 FD SAGE Publications VO 9 IS 4 SP 12 OP 13 DO 10.1177/155989770904005 UL http://mdc.sagepub.com/content/9/4/12.2.abstract AB In the Atrial Fibrillation Clopidogrel Trial with Irbesartan for Prevention of Vascular Events [ACTIVE-I; NCT00249795], treatment with irbesartan failed to lower the risk of stroke, myocardial infarction, and vascular death compared with placebo in patients with atrial fibrillation (AF). However, irbesartan may have a role in preventing heart failure, recurrent embolic events, and cardiovascular hospitalizations in patients with AF.