RT Journal Article SR Electronic A1 Vinall, Phil T1 Replacement of Lost CNS Function JF MD Conference Express YR 2008 FD SAGE Publications VO 8 IS 1 SP 22 OP 29 DO 10.1177/155989770800800115 UL http://mdc.sagepub.com/content/8/1/22.abstract AB This article discusses updates in stroke recovery therapies, including an overview of the current state of Functional Electrical Stimulation, which is the use of electrical stimulation (via a neuroprosthesis) to activate muscles in a specific programmed sequence to allow the functional use of a limb that has been affected by stroke or spinal cord injury. Also discussed are advances in the BrainGate Neural Interface System, and the development of an interactive robot-assisted neuro-rehabilitation system called RUPERT (Robotic Upper Extremity Repetitive Trainer).