RT Journal Article SR Electronic A1 Vinall, Phil T1 Results of EPITHET JF MD Conference Express YR 2008 FD SAGE Publications VO 8 IS 1 SP 11 OP 12 DO 10.1177/155989770800800106 UL http://mdc.sagepub.com/content/8/1/11.abstract AB Intravenous recombinant tissue plasminogen activator (tPA) is recommended for the treatment of acute ischemic stroke within the first 3 hours of stroke onset. The objective of the Echoplanar Imaging Thrombolytic Evaluation Trial [EPITHET] was to evaluate the effect of the administration of tPA 3–6 hours after stroke onset as measured by echoplanar magnetic resonance imaging (MRI), diffusion-weighted MRI, and perfusion-weighted MRI.