RT Journal Article SR Electronic A1 Jacobson, Anne T1 Pioglitazone May Be Effective in Reducing Progression of Atherosclerosis in Patients with Diabetes JF MD Conference Express YR 2008 FD SAGE Publications VO 8 IS 2 SP 15 OP 15 DO 10.1177/155989770800800212 UL http://mdc.sagepub.com/content/8/2/15.1.abstract AB Although coronary artery disease accounts for 75% of deaths in patients with diabetes, few studies have compared antidiabetic agents beyond their glucose-lowering efficacy. The prospective, randomized PERISCOPE trialtrial showed that an insulin-sensitizing drug (pioglitazone) may be more effective than a traditional insulin secretagogue (glimepiride) in stopping or reducing the progression of atherosclerosis.