PT - JOURNAL ARTICLE AU - Jacobson, Anne ED - Nissen, Steven TI - Pioglitazone May Be Effective in Reducing Progression of Atherosclerosis in Patients with Diabetes DP - 2008 Jun 01 TA - MD Conference Express PG - 15--15 VI - 8 IP - 2 4099 - http://mdc.sagepub.com/content/8/2/15.1.short 4100 - http://mdc.sagepub.com/content/8/2/15.1.full AB - Although coronary artery disease accounts for 75% of deaths in patients with diabetes, few studies have compared antidiabetic agents beyond their glucose-lowering efficacy. The prospective, randomized PERISCOPE trialtrial showed that an insulin-sensitizing drug (pioglitazone) may be more effective than a traditional insulin secretagogue (glimepiride) in stopping or reducing the progression of atherosclerosis.