PT  - JOURNAL ARTICLE
AU  - Canavan, Neil
ED  - Punt, Cornelis J.
TI  - Combination Biologic Therapy in Advanced Colorectal Cancer
DP  - 2008 Aug 01
TA  - MD Conference Express
PG  - 10--10
VI  - 8
IP  - 4
4099  - http://mdc.sagepub.com/content/8/4/10.short
4100  - http://mdc.sagepub.com/content/8/4/10.full
AB  - The addition of a vascular endothelial growth factor antibody and an epidermal growth factor receptor inhibitor to chemotherapy had no benefit in advanced colorectal cancer. In fact, the combination had a significantly negative effect on progression-free survival. This article discusses the results of CAIRO2 [NCT00208546], a trial that was designed to investigate the effect of adding cetuximab to chemotherapy plus bevacizumab.